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Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

Distinctive Capillary Action by Micro-channels in Bone-like Templates can Enhance Recruitment of Cells for Restoration of Large Bony Defect

DOI:
10.3791/52947-v

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09:35 min

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September 11, 2015

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, , , , , ,
1Oral and Maxillofacial Surgery,Columbia University, 2Endodontics,Columbia University, 3Mechanical Engineering,Kyung Hee University, South Korea, 4Orthodontics,The Ohio State University, 5Pathology,Weill Cornell Medical College

Chapters

  • 00:05Title
  • 01:29Polyurethane Sponge Template Preparation
  • 02:32Hydroxyapatite Slurry Coating Preparation
  • 04:43Hydroxyapatite Coating, Drying, and Sintering
  • 05:52Ingress and Inhabitancy of Cells into the Template
  • 07:46Results: The Biogenic Microenvironment Template Supports Cell Mobilization and Proliferation
  • 08:54Conclusion

Summary

Automatic Translation

Automatic Translation

A step-by-step generic process to create a bone-like template with engineered micro-channels is presented. High absorption and retention capabilities of the template are demonstrated by capillary action via micro-channels.

Tags

Keywords: Capillary ActionMicro-channelsBone-like TemplatesCell RecruitmentBone RegenerationTrabecular BoneBiogenic Microenvironment Template (BMT)Mechanical StrengthCell InfiltrationCell DistributionCell MigrationBone Marrow CellsGrowth FactorsSkeletal Defects

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