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JoVE Journal
Bioengineering

This content is Open Access.

Engineered 3D Silk-collagen-based Model of Polarized Neural Tissue
 

Engineered 3D Silk-collagen-based Model of Polarized Neural Tissue

Article doi: 10.3791/52970
October 23rd, 2015

Summary October 23rd, 2015

Insight into the complex actions of the brain requires advanced research tools. Here we demonstrate a novel silk-collagen-based 3D engineered model of neural tissue resembling brain-like architecture. The model can be used to study neuronal network assembly, axonal guidance, cell-cell interactions and electrical activity.

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