JoVE Journal
Medicine
Medicine
A subscription to JoVE is required to view this content.
You will only be able to see the first 2 minutes.
Chapters
Summary August 18th, 2015
Thromboembolic stroke models are vital tools for optimizing the recanalization therapy. Here we report a murine thrombotic stroke model based on transient cerebral hypoxic-ischemic (tHI) insult, which triggers thrombosis and infarction, and responds favorably to tissue plasminogen activator (tPA)-mediated fibrinolysis in a therapeutic window similar to those in stroke patients.
