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JoVE Journal Bioengineering
Minced Tissue in Compressed Collagen
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Minced Tissue in Compressed Collagen: A Cell-containing Biotransplant for Single-staged Reconstructive Repair

Article DOI: 10.3791/53061-v • 09:43 min • February 24th, 2016
February 24th, 2016 •
1, 1,2, 1,2, 1,2
1Department of Women's and Children's Health, Center for Molecular Medicine, Karolinska Institutet, 2Department of Pediatric Surgery, Urology Section, Astrid Lindgren Children's Hospital, Karolinska University Hospital

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Summary
Automatic Translation

Tissue engineering often includes in vitro expansion in order to create autografts for tissue regeneration. In this study a method for tissue expansion, regeneration, and reconstruction in vivo was developed in order to minimize the processing of cells and biological materials outside the body.

Tags

Minced Tissue Compressed Collagen Biotransplant Reconstructive Repair Autologous Tissue Biopsy Polycapro-lactone PCL Collagen Autograft 3D Scaffold Transplantation Immunohistochemical Analysis Proliferation Reorganization Animal Model Skin Urothelium Severely Malformed Tissues Trauma Surgical Repair In Vitro Culturing One-stage Surgical Procedure Sterile Conditions Porcine Bladder Biopsy Specimen
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