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Method of Studying Palatal Fusion using Static Organ Culture
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Method of Studying Palatal Fusion using Static Organ Culture
DOI:

04:58 min

September 19, 2015

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Chapters

  • 00:05Title
  • 01:09Mouse Embryo Collection
  • 02:03Palate Dissection and Culture
  • 03:38Results: The Effects of Nicotine Treatment on Murine Palatal Fusion
  • 04:30Conclusion

Summary

Automatic Translation

Studies of palate development are motivated by the incidence of cleft palate, a birth defect that imposes a tremendous health burden and can leave lasting disfigurement. We demonstrate here a technique to culture palatal shelves that can be used to study different signaling pathways involved in palatal development and fusion.

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