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Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications
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Bioengineering
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JoVE Journal Bioengineering
Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications

Solid Lipid Nanoparticles (SLNs) for Intracellular Targeting Applications

DOI:
10.3791/53102-v

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08:19 min

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November 17, 2015

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, , ,
1Research and Exploratory Development Department,The Johns Hopkins Applied Physics Laboratory, 2Department of Plastic and Reconstructive Surgery,Johns Hopkins School of Medicine, 3Asymmetric Operations Sector,The Johns Hopkins Applied Physics Laboratory

Chapters

  • 00:05Title
  • 01:41Processing of SLNs
  • 04:10SLNs Interaction with Fibroblasts
  • 06:26Results: SLN Characterization and Interaction with Cellular Models
  • 07:50Conclusion

Summary

Automatic Translation

Automatic Translation

In this study, a method for synthesizing ultra-small populations of biocompatible nanoparticles was described, as well as several in vitro methods by which to assess their cellular interactions.

Tags

Keywords: Solid Lipid Nanoparticles (SLNs)Intracellular TargetingNanoparticle DeliveryFluorescent DyePhase Inversion Temperature (PIT) MethodBiocompatible NanoparticlesMTT AssayHuman Dermal FibroblastsMouse Dendritic CellsParticle UptakeFluorescence MicroscopyFlow Cytometry

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