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Chronic Constriction Injury of the Rat’s Infraorbital Nerve (IoN-CCI) to Study Trigeminal Neuropathic Pain
JoVE Journal
Medicine
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JoVE Journal Medicine
Chronic Constriction Injury of the Rat’s Infraorbital Nerve (IoN-CCI) to Study Trigeminal Neuropathic Pain
DOI:

10:52 min

September 21, 2015

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Chapters

  • 00:05Title
  • 01:49IoN Constriction Surgery
  • 05:17Facial Grooming Behavioral Test
  • 06:25Analysis of the Facial Grooming Data
  • 07:26The Mechanical Stimulation Test
  • 09:39Post-IoN Constriction Behavioral Changes
  • 10:20Conclusion

Summary

Automatic Translation

This manuscript describes a rodent model to study trigeminal neuropathic pain. The methods described include surgical procedures to perform a chronic constriction injury of the rat’s infraorbital nerve and the post-surgical behavioral tests to measure the changes in spontaneous and evoked behavior that are indicative of persistent pain and allodynia.

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