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Chronic Constriction Injury of the Rat's Infraorbital Nerve (IoN-CCI) to Study Trigeminal Neuropathic Pain

Article DOI: 10.3791/53167
September 21st, 2015 •
1, 2
1Translational Neurosciences, University of Antwerp, 2Multidisciplinary Pain Center, Antwerp University Hospital

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September 21st, 2015

This manuscript describes a rodent model to study trigeminal neuropathic pain. The methods described include surgical procedures to perform a chronic constriction injury of the rat’s infraorbital nerve and the post-surgical behavioral tests to measure the changes in spontaneous and evoked behavior that are indicative of persistent pain and allodynia.

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