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Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease
<em>Ex Vivo</em> Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease
JoVE Journal
Medicine
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JoVE Journal Medicine
Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease

Ex Vivo Intestinal Sacs to Assess Mucosal Permeability in Models of Gastrointestinal Disease

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06:04 min

February 09, 2016

DOI:

06:04 min
February 09, 2016

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Summary

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This protocol describes the use of excised intestinal tissue preparations or "intestinal sacs" as an ex vivo model of intestinal barrier function. This model may be used to assess integrity of both the epithelial barrier and the mucous gel layer at specific intestinal sites in animal models of digestive disease.

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