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A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
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Behavior
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JoVE Journal Behavior
A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration

DOI:
10.3791/53266-v

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09:16 min

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January 22, 2016

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, , ,
1Department of Neurosurgery,Louisiana State University, 2Department of Pharmacology, Toxicology, and Neuroscience,Louisiana State University

Chapters

  • 00:05Title
  • 01:13Intravenous (IV) Methamphetamine Self-Administration
  • 03:40Brain Stimulation Apparatus and Stimulation Programming
  • 05:43Deep Brain Stimulation Experiment
  • 07:16Results: Deep Brain Stimulation Reduces Operant Methamphetamine Self-Administration in Rats
  • 08:19Conclusion

Summary

Automatic Translation

Automatic Translation

This article describes the delivery of intracranial electrical stimulation that is temporally and spatially separate from the drug-use environment for the treatment of IV methamphetamine dependence.

Tags

Keywords: Deep Brain StimulationIntravenous Methamphetamine Self-administrationAddiction PsychiatryOperant ChambersDrug Use EnvironmentFixed Ratio ScheduleLever PressMethamphetamine InfusionTimeout PeriodStable Responding

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