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JoVE Journal
Immunology and Infection

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An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics
 

An Endothelial Planar Cell Model for Imaging Immunological Synapse Dynamics

Article DOI: 10.3791/53288
December 24th, 2015

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Summary December 24th, 2015

Adaptive immunity is controlled by dynamic 'immunological synapses' formed between T cells and antigen presenting cells. This protocol describes methods for investigating endothelial cells both as understudied physiologic APCs and as a novel type of 'planar cellular APC model'.

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