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Apical Resection Mouse Model to Study Early Mammalian Heart Regeneration
JoVE Journal
Medicine
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JoVE Journal Medicine
Apical Resection Mouse Model to Study Early Mammalian Heart Regeneration
DOI:

06:08 min

January 23, 2016

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Chapters

  • 00:05Title
  • 00:47Hypothermia Anesthesia and Thoracotomy
  • 01:45Surgical Amputation of the Heart Ventricular Apex
  • 02:06Suture and Recovery
  • 02:58Post-Surgical Analysis
  • 04:32Results: Representative H&E and Masson’s Trichrome Staining
  • 05:25Conclusion

Summary

Automatic Translation

A step-by-step video protocol of apical resection is demonstrated in this study. Apical resection is a recently highlighted surgical approach in mammalian heart regeneration research. This study may promote the application of apical resection as a standard methodology in research into the mechanism underlying heart regeneration.

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