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April 26, 2016
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The most commonly used method for nanostructured lipid carrier (NLC) synthesis involves oil-in-water emulsion, homogenization and solidification. This was modified here by applying high shear dispersion after solidification to achieve a NLC with desirable size, improved drug encapsulation and drug loading efficiency as a potential carrier for dacarbazine delivery.
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Cite this Article
Almoussalam, M., Zhu, H. Encapsulation of Cancer Therapeutic Agent Dacarbazine Using Nanostructured Lipid Carrier. J. Vis. Exp. (110), e53760, doi:10.3791/53760 (2016).
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