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Transcutaneous Assessment of Renal Function in Conscious Rodents
JoVE Journal
Medicine
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JoVE Journal Medicine
Transcutaneous Assessment of Renal Function in Conscious Rodents

Transcutaneous Assessment of Renal Function in Conscious Rodents

DOI:
10.3791/53767-v

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07:18 min

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March 26, 2016

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, ,
1Medical Research Center,Medical Faculty Mannheim, University of Heidelberg

Chapters

  • 00:05Title
  • 01:03Device Fixation to Animal
  • 03:50FITC-sinistrin Administration and Fluorescence Measurement
  • 05:35Results: Representative FITC-sinstrin Elmination Curve in Animals with Impaired Renal Function
  • 06:41Conclusion

Summary

Automatic Translation

Automatic Translation

Determination of glomerular filtration rate (GFR) is the gold standard to assess overall kidney function. However, traditional procedures to measure this parameter are cumbersome and require a large investment of time. Here we describe a faster and minimally invasive method to determinate GFR transcutaneously.

Tags

Keywords: Transcutaneous AssessmentRenal FunctionConscious RodentsMinimally InvasiveSequential MeasurementsAnesthesiaFur RemovalOptical DeviceAdhesive PatchTubular Elastic Gauze BandageMovement Artifacts

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