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Development of an In Vitro Ocular Platform to Test Contact Lenses
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Bioengineering
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JoVE Journal Bioengineering
Development of an In Vitro Ocular Platform to Test Contact Lenses

Development of an In Vitro Ocular Platform to Test Contact Lenses

DOI:
10.3791/53907-v

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08:28 min

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April 06, 2016

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, , , , ,
1School of Optometry and Vision Science,University of Waterloo, 2Medella Health

Chapters

  • 00:05Title
  • 01:04Synthesizing Eyepieces from PDMS and Agarose
  • 02:55Incorporating a Bovine Cornea on the PDMS Eyeball
  • 05:12Blink Platform Assembly
  • 06:32Results: Contact Lens Antibiotic Release and Cholesterol Deposition, Comparing Models
  • 07:31Conclusion

Summary

Automatic Translation

Automatic Translation

Current in vitro models for evaluating contact lenses (CLs) and other eye-related applications are severely limited. The presented ocular platform simulates physiological tear flow, tear volume, air exposure and mechanical wear. This system is highly versatile and can be applied to various in vitro analyses with CLs.

Tags

In Vitro Ocular PlatformContact Lens TestingTear VolumeTear FlowAir ExposureMechanical WearBlinking SimulationOphthalmic Device TestingPDMSAgaroseEyeball ModelEyelid ModelMicrofluidicsOphthalmic Research

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