Journal
/
Behavior
/
A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test
JoVE Journal
Behavior
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Behavior
A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

A Novel Approach to Assess Motor Outcome of Deep Brain Stimulation Effects in the Hemiparkinsonian Rat: Staircase and Cylinder Test

DOI:
10.3791/53951-v

•

07:14 min

•

May 31, 2016

•

, , , ,
1Department of Neurology,University Hospital Wuerzburg, 2Institute of Anatomy and Cell Biology,University Wuerzburg

Chapters

  • 00:05Title
  • 00:51Cylinder Test
  • 02:18Staircase Test
  • 05:05Results: Hemiparkinsonian Rat Performance with Deep Brain Stimulation
  • 06:18Conclusion

Summary

Automatic Translation

Automatic Translation

Deep brain stimulation (DBS) is an effective treatment option for Parkinson's disease. We established a study design to screen novel stimulation paradigms in rats. The protocol describes the use of the staircase test and cylinder test for motor outcome assessment in DBS treated hemiparkinsonian rats.

Tags

Keywords: Motor OutcomeDeep Brain StimulationHemiparkinsonian RatStaircase TestCylinder TestPaw Use AsymmetryBehavioral AssessmentCircadian DifferencesRearingPellet Reward

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/53951?article_type=v

Stereotactic Injection of MicroRNA-expressing Lentiviruses to the Mouse Hippocampus CA1 Region and Assessment of the Behavioral Outcome
check_url/53951?article_type=v

Paw-Dragging: a Novel, Sensitive Analysis of the Mouse Cylinder Test
check_url/53951?article_type=v

Vagus Nerve Stimulation as a Tool to Induce Plasticity in Pathways Relevant for Extinction Learning
check_url/53951?article_type=v

A General Method for Evaluating Deep Brain Stimulation Effects on Intravenous Methamphetamine Self-Administration
check_url/53951?article_type=v

Non-Invasive Electrical Brain Stimulation Montages for Modulation of Human Motor Function
check_url/53951?article_type=v

A Novel Experimental and Analytical Approach to the Multimodal Neural Decoding of Intent During Social Interaction in Freely-behaving Human Infants
check_url/53951?article_type=v

Repetitive Transcranial Magnetic Stimulation to the Unilateral Hemisphere of Rat Brain
check_url/53951?article_type=v

Sit-to-stand-and-walk from 120% Knee Height: A Novel Approach to Assess Dynamic Postural Control Independent of Lead-limb
check_url/53951?article_type=v

Behavioral Disturbances: An Innovative Approach to Monitor the Modulatory Effects of a Nutraceutical Diet
check_url/53951?article_type=v

A Within-subjects Experimental Protocol to Assess the Effects of Social Input on Infant EEG

Read Article