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Design and Development of Aptamer–Gold Nanoparticle Based Colorimetric Assays for In-the-field Applications

Article DOI: 10.3791/54063-v • 08:23 min • June 23rd, 2016
June 23rd, 2016 •
1, 2,3, 2, 2
1Department of Science and Mathematics, Alvernia University, 2711th Human Performance Wing, Air Force Research Laboratory, Wright-Patterson Air Force Base, 3UES, Inc.

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Summary
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The design and development of an aptamer–gold nanoparticle colorimetric assay for the detection of small molecules for in-the-field applications was examined. Additionally, a smart-device colorimetric application (app) was validated and long-term storage of the assay was established for use in the field.

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Aptamer-gold Nanoparticle Colorimetric Assays In-the-field Applications Detection Of Target Molecules Long-term Storage False Positive Response Rates Reproducibility Shelf-life Acid Wash Gold Three Chloride Sodium Citrate Color Change
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