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JoVE Journal
Bioengineering

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Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes
 

Delivery of Therapeutic siRNA to the CNS Using Cationic and Anionic Liposomes

Article DOI: 10.3791/54106
July 23rd, 2016

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Summary July 23rd, 2016

The goal of this protocol is to use cationic/anionic liposomes with a neuro-targeting peptide as a CNS delivery system to enable siRNA to cross the BBB. The optimization of a delivery system for treatments, like siRNA, would allow for more treatment options for prion and other neurodegenerative diseases.

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