We present an approach for visualizing fluorescent protein DNA binding peptide (FP-DBP)-stained large DNA molecules tethered on the polyethylene glycol (PEG) and avidin-coated glass surface and stretched with microfluidic shear flows.
Lee, S., Jo, K. Visualization of Surface-tethered Large DNA Molecules with a Fluorescent Protein DNA Binding Peptide. J. Vis. Exp. (112), e54141, doi:10.3791/54141 (2016).