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Chapters
- 00:05Title
- 00:48Limb Ischemia Induction
- 05:55Results: Perfusion Imaging Variations after Hindlimb Ischemia Induction
- 06:54Conclusion
Surgical induction of hindlimb ischemia in the mouse is useful to examine angiogenesis, however this is compromised in certain inbred mouse strains that display marked ischemia-induced tissue necrosis. Methods are described to induce subacute limb ischemia using ameroid constrictors to circumvent this problem through the induction of gradual arterial occlusion.
