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Medicine

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Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
 

Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats

Article DOI: 10.3791/54830
April 21st, 2017

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Summary April 21st, 2017

Neonatal stroke is a significant cause of early brain injury requiring a translational model with consistent focal injury patterns and high reproducibility in order to enable study. This study describes the detailed surgical procedure for creating a non-hemorrhagic, unilateral focal ischemia-reperfusion injury in full-term-equivalent rodents.

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