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Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses
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Immunology and Infection
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JoVE Journal Immunology and Infection
Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses

Increased Recovery Time and Decreased LPS Administration to Study the Vagus Nerve Stimulation Mechanisms in Limited Inflammatory Responses

DOI:
10.3791/54890-v

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06:43 min

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March 29, 2017

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, , ,
1Department of Medicine, Unit of Rheumatology, Center for Molecular Medicine (CMM), Karolinska Institute,Karolinska University Hospital

Chapters

  • 00:05Title
  • 01:31Preparation for Surgery
  • 02:44Vagus Nerve Stimulation
  • 04:46Results: Cytokine Levels in Spleen of Vagus Nerve Stimulated Animals and Controls
  • 05:37Conclusion

Summary

Automatic Translation

Automatic Translation

Vagus nerve stimulation has proven to have a strong efficacy for decreasing peripheral inflammation. Here, we present a modified vagus nerve stimulation protocol that allows for further examinations of the cholinergic anti-inflammatory mechanisms in limited inflammatory responses.

Tags

Keywords: Vagus Nerve StimulationInflammatory ResponseCholinergic Anti-inflammatory PathwayNeuroimmunologyLipopolysaccharide (LPS)Mouse SurgeryAnesthesiaSternocleidomastoid MuscleCarotid Artery

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