Magnetic Levitation Coupled with Portable Imaging and Analysis for Disease Diagnostics

The overall goal of this process is to perform density-based cellular analysis for various medical diagnostic applications by measuring the altered distribution of a cell population or by separating cell types based on their characteristic densities. This method can help solve a key challenge in biomedical engineering to perform important cell ways medical diagnostics in clinical settings or developing countries. The main advantage of this technique is that it does not require a lot of equipment or preparation and it can be done by almost anyone.

The implications of this technique extend toward sickle cell diagnosis because this device can quantify the increased density and decreased levitation rate caused by low oxygen conditions in sickle cells. Though this method is useful for medical diagnostic tests as demonstrated here, it can also be applied to other density based cytometric tests by altering the sample and modifying the software. First, prepare 10 milliliters of a 50 millimolar solution of gadobutrol and Hanks balanced salt solution.