Journal
/
Medicine
/
Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes in Administration Sets Using a Pump

DOI:
10.3791/55086-v

•

06:08 min

•

March 11, 2017

•

, , , ,
1College of Pharmacy,Yonsei University, 2College of Medicine,Yonsei University, 3Yonsei Institute of Pharmaceutical Sciences, 4Polyscientech Co. Ltd

Chapters

  • 00:05Title
  • 00:56Preparation of Tubes and Drug Injections
  • 01:41Kinetic Sorption Study Using an Infusion Pump
  • 02:45Analysis of Drug Using High-performance Liquid Chromatography
  • 03:32Results: Evaluation of Drug Sorption to PVC- and Non-PVC-based Tubes
  • 04:33Conclusion

Summary

Automatic Translation

Automatic Translation

We report a method for drug sorption evaluation using a pump and model drugs (diazepam and tacrolimus). After drug analysis using high-performance liquid chromatography, drug concentrations and sorption levels in the tubes of administration sets are calculated.

Tags

Keywords: Drug SorptionPVCNon-PVCAdministration SetsInfusion PumpTubeDrug SolutionHPLCUV DetectionCalibration CurveSample Collection

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/55086?article_type=v

Femoral Arterial and Venous Catheterization for Blood Sampling, Drug Administration and Conscious Blood Pressure and Heart Rate Measurements
check_url/55086?article_type=v

A Novel Surgical Approach for Intratracheal Administration of Bioactive Agents in a Fetal Mouse Model
check_url/55086?article_type=v

Intranasal Administration of CNS Therapeutics to Awake Mice
check_url/55086?article_type=v

Evaluation of a Novel Laser-assisted Coronary Anastomotic Connector – the Trinity Clip – in a Porcine Off-pump Bypass Model
check_url/55086?article_type=v

Quantification of the Immunosuppressant Tacrolimus on Dried Blood Spots Using LC-MS/MS
check_url/55086?article_type=v

Using Multi-fluorinated Bile Acids and In Vivo Magnetic Resonance Imaging to Measure Bile Acid Transport
check_url/55086?article_type=v

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
check_url/55086?article_type=v

Novel Methods for Intranasal Administration Under Inhalation Anesthesia to Evaluate Nose-to-Brain Drug Delivery
check_url/55086?article_type=v

Implantation of an Isoproterenol Mini-Pump to Induce Heart Failure in Mice
check_url/55086?article_type=v

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Read Article