Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

Hilda Vargas Robles; Karla Fabiola Castro Ochoa; Porfirio Nava; Ang&#233;lica Silva Olivares; Mineko Shibayama; Michael Schnoor

doi:10.3791/55095

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Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

JoVE Journal
Medicine

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JoVE Journal Medicine

Analyzing Beneficial Effects of Nutritional Supplements on Intestinal Epithelial Barrier Functions During Experimental Colitis

12,240 Views

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08:58 min

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January 05, 2017

DOI:

10.3791/55095-v

DOI:

10.3791/55095-v

•

08:58 min

January 05, 2017

•

12219 Views

Hilda Vargas Robles¹, Karla Fabiola Castro Ochoa¹, Porfirio Nava², Angélica Silva Olivares³, Mineko Shibayama³, Michael Schnoor¹

¹Department of Molecular Biomedicine,Center for Research and Advanced Studies of the National Polytechnic Institute ²Department of Physiology, Biophysics and Neurosciences,Center for Research and Advanced Studies of the National Polytechnic Institute ³Department of Infectomics and Molecular Pathogenesis,Center for Research and Advanced Studies of the National Polytechnic Institute

Summary

Current treatments of inflammatory bowel diseases (IBD) aim at alleviating disease symptoms but may cause severe side effects. Thus, alternative strategies are being investigated in animal colitis models. Here, we explain how the beneficial effects of diet supplements on clinical IBD signs are analyzed in such a colitis model.