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JoVE Journal
Medicine

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Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity (AIDN)
 

Use of a Piglet Model for the Study of Anesthetic-induced Developmental Neurotoxicity (AIDN): A Translational Neuroscience Approach

Article DOI: 10.3791/55193
June 11th, 2017

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Summary June 11th, 2017

Anesthesia-induced developmental neurotoxicity (AIDN) research has focused on rodents, which are not broadly applicable to humans. Non-human primate models are more relevant, but are cost-prohibitive and difficult to use for experimentation. The piglet, in contrast, is a clinically relevant, practical animal model ideal for the study of anesthetic neurotoxicity.

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