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Lokal Feltet Fluorescensmikroskopi: Imaging Cellular Signaler i Intakte Hearts

Article DOI: 10.3791/55202-v • 10:33 min • March 8th, 2017
March 8th, 2017 •
*1, *2,3, 4, 5
1School of Natural Sciences, University of California, Merced, 2Centro de Investigaciones Cardiovasculares, Universidad de la Plata and Conicet, 3Facultad de Ingenieria, Universidad Nacional de Entre Rios, 4Department of Physiology, Midwestern University, 5School of Engineering, University of California, Merced
* These authors contributed equally

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I hjertet, molekylære hendelser som koordinerer den elektriske og kontraktile funksjon av organet. Et sett av lokale felt fluorescens-mikroskopi teknikker som presenteres her muliggjør opptak av cellulære variabler i intakte hjertet. Identifisere mekanismer som definerer hjertefunksjonen er avgjørende for å forstå hvordan hjertet fungerer under patologiske situasjoner.

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Cellular Biology Intakt hjerte fluorescens pulset lokale feltet kalsium aksjonspotensiale Rhod-2 di-8-ANEPPS
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