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The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions
JoVE Journal
Bioengineering
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JoVE Journal Bioengineering
The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

The Use of a β-lactamase-based Conductimetric Biosensor Assay to Detect Biomolecular Interactions

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08:06 min

February 01, 2018

DOI:

08:06 min
February 01, 2018

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Summary

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In this work, we report a new method to study protein-protein interactions using a conductimetric biosensor based on the hybrid β-lactamase technology. This method relies on release of protons upon hydrolysis of β-lactams.

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