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Genetics

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Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
 

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Article doi: 10.3791/55501
May 24th, 2017

Summary May 24th, 2017

Here, the study of different DNA lesion recognition approaches via single molecule AFM imaging is demonstrated with the nucleotide excision repair system as an example. The procedures of DNA and protein sample preparations and experimental as well as analytical details for the AFM experiments are described.

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