Sialic acid is a typical monosaccharide-unit found in glycoconjugates. It is involved in a plethora of molecular and cellular interactions. Here we present a method to modify cell surface sialic acid expression using metabolic glycoengineering with N-acetylmannosamine derivatives.
Wratil, P. R., Horstkorte, R. Metabolic Glycoengineering of Sialic Acid Using N-acyl-modified Mannosamines. J. Vis. Exp. (129), e55746, doi:10.3791/55746 (2017).