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Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling
Chemo-enzymatic Synthesis of <em>N</em>-glycans for Array Development and HIV Antibody Profiling
JoVE Journal
Chemistry
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JoVE Journal Chemistry
Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

Chemo-enzymatic Synthesis of N-glycans for Array Development and HIV Antibody Profiling

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11:08 min

February 05, 2018

DOI:

11:08 min
February 05, 2018

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Summary

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A modular approach to the synthesis of N-glycans for attachment to an aluminum oxide-coated glass slide (ACG slide) as a glycan microarray has been developed and its use for the profiling of an HIV broadly neutralizing antibody has been demonstrated.

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