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Cancer Research

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Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia
 

Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia

Article doi: 10.3791/55901
July 25th, 2017

Summary July 25th, 2017

Mosaic clone analysis in Drosophila imaginal disc epithelia is a powerful model system to study the genetic and cellular mechanisms of tumorigenesis. Here we describe a protocol to induce tumors in Drosophila wing imaginal discs using the GAL4-UAS system, and introduce a diagnosis method to classify the tumor phenotypes.

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