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JoVE Journal
Cancer Research

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Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia
 

Induction and Diagnosis of Tumors in Drosophila Imaginal Disc Epithelia

Article DOI: 10.3791/55901 08:14 min July 25th, 2017
July 25th, 2017

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Summary

Mosaic clone analysis in Drosophila imaginal disc epithelia is a powerful model system to study the genetic and cellular mechanisms of tumorigenesis. Here we describe a protocol to induce tumors in Drosophila wing imaginal discs using the GAL4-UAS system, and introduce a diagnosis method to classify the tumor phenotypes.

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Tags

Induction Diagnosis Tumors Drosophila Imaginal Disc Epithelia Tumerogenic Mosaic Clones Tumor Development Stages Cancer Modeling Tumor Injection Fly Genetics Classification Genetic Cross Virgins Pupae Incubation Heat-shock Larvae
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