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Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze
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Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze

Assessing Spatial Memory Impairment in a Mouse Model of Traumatic Brain Injury Using a Radial Water Tread Maze

DOI:
10.3791/55986-v

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06:09 min

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July 17, 2017

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, , , , ,
1Department of Radiology,University of Washington, 2Department of Radiology,University of Utah, 3Geriatric Research Education and Clinical Center (GRECC),VA Puget Sound

Chapters

  • 00:05Title
  • 00:54Preparing the Radial Water Tread Maze
  • 02:11Testing Protocol
  • 04:21Results: Using the Radial Water Maze to Measure Learning in TBI Mice
  • 05:33Conclusion

Summary

Automatic Translation

Automatic Translation

Here we present a protocol for a mouse-specific test of cognition that does not require swimming. This test can be used to successfully distinguish controlled cortical impact-induced traumatic brain injury mice from sham controls.

Tags

Keywords: Spatial MemoryRadial Water Tread MazeTraumatic Brain InjuryMouse ModelCognitive TestingMorris Water MazeEscape BoxVisual CuesWater TemperatureLightingTrial Duration

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