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JoVE Journal
Genetics

This content is Open Access.

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping
 

High-resolution Melting PCR for Complement Receptor 1 Length Polymorphism Genotyping: An Innovative Tool for Alzheimer's Disease Gene Susceptibility Assessment

Article doi: 10.3791/56012
July 18th, 2017

Summary July 18th, 2017

Here, we describe an innovative method to determine complement receptor 1 (CR1) length polymorphisms for use in several applications, particularly the assessment of susceptibility to diseases such as Alzheimer's disease (AD). This method could be useful to better understand the role of CR1 isoforms in the pathogenesis of AD.

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