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JoVE Journal
Cancer Research

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Detection of Rare Mutations in CtDNA Using Next Generation Sequencing
 

Detection of Rare Mutations in CtDNA Using Next Generation Sequencing

Article DOI: 10.3791/56342
August 24th, 2017

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Summary August 24th, 2017

This manuscript describes a technique for detecting mutations of low frequency in ctDNA, ER-Seq. This method is differentiated by its unique use of two-directional error correction, a special background filter, and efficient molecular acquirement.

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