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JoVE Journal
Neuroscience

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JoVE Journal Neuroscience
Un approccio semplice per indurre la neurite Autoimmune Sperimentale in topi C57BL/6 per le valutazioni funzionali e Neuropathological
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Un approccio semplice per indurre la neurite Autoimmune Sperimentale in topi C57BL/6 per le valutazioni funzionali e Neuropathological

Article DOI: 10.3791/56455
November 9th, 2017 •
1, 1, 1, 1, 1, 1
1Department of Anatomy and Neuroscience, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne

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November 9th, 2017

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Questo rapporto descrive un approccio semplice per indurre con successo la neurite autoimmune sperimentale (EAN) utilizzando la proteina della mielina zero (P0)180-199 del peptide in combinazione con adiuvante completo di Freund e tossina della pertosse. Vi presentiamo un paradigma sofisticato in grado di valutare con precisione l'entità dei deficit funzionali e neuropatologia che si verificano in questo EAN.

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