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JoVE Journal
Cancer Research

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Looking for Driver Pathways of Acquired Resistance to Targeted Therapy
 

Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down

Article DOI: 10.3791/56583
December 11th, 2017

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Summary December 11th, 2017

This is a time- and cost-effective in vitro protocol investigating the mechanisms of acquired resistance to targeted therapeutic agents, which is a highly unmet medical need in cancer management.

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