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December 11, 2017
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This is a time- and cost-effective in vitro protocol investigating the mechanisms of acquired resistance to targeted therapeutic agents, which is a highly unmet medical need in cancer management.
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Cite this Article
Arienti, C., Pignatta, S., Zanoni, M., Cortesi, M., Zamagni, A., Piccinini, F., Tesei, A. Looking for Driver Pathways of Acquired Resistance to Targeted Therapy: Drug Resistant Subclone Generation and Sensitivity Restoring by Gene Knock-down. J. Vis. Exp. (130), e56583, doi:10.3791/56583 (2017).
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