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Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Orthotopic Ovarian Transplantation Procedures to Investigate the Life- and Health-span Influence of Ovarian Senescence in Female Mice
DOI:

06:49 min

February 12, 2018

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Chapters

  • 00:04Title
  • 00:59Intact Ovary Harvest
  • 03:32Intact Ovary Transplantation
  • 04:56Results: Representative Effects of Ovarian Transplant and Small Follicle Depletion in CBA/J Mice
  • 06:21Conclusion

Summary

Automatic Translation

Described here are orthotopic ovarian transplantation protocols for modifying ovarian influence on the physiology of the recipient mouse. This surgical procedure is used to expose female mice to various types of ovarian influence and may include heterochronic transplantations and transplantation of ovaries that have undergone various ex vivo treatments.

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