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Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy
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Subretinal Transplantation of Human Embryonic Stem Cell Derived-retinal Pigment Epithelial Cells into a Large-eyed Model of Geographic Atrophy

Article DOI: 10.3791/56702-v • 11:03 min • January 22nd, 2018
January 22nd, 2018 •
*1,2, *1, 1, 1, 2, 1
1Clinical Neuroscience, Section for Ophtalmology and Vision, Karolinska Institutet, 2Clinical Sciences, Intervention and Technology, Division of Obstetrics and Gynecology, Karolinska Institutet
* These authors contributed equally

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Summary
Automatic Translation

Retinal pigment epithelial cells could serve as a cell-replacement therapy for the advanced form of dry age-related macular degeneration. This protocol describes the generation of a large-eyed model of geographic atrophy and the subretinal transplantation of human embryonic stem cell-derived retinal pigment epithelial cells into this model of disease.

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Subretinal Transplantation Human Embryonic Stem Cells Retinal Pigment Epithelial Cells Large-eyed Model Geographic Atrophy Regenerative Medicine Stem Cell Treatment Degenerative Diseases Surgical Setting Subretinal Injection Age-related Macular Degeneration Rabbit Optical Coherence Tomography Lid Retractor Nictitans Membrane Microsurgery Transvitreal Pars Plana Technique
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