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Journal / Bioengineering / Vergelijkbare Decellularization van foetale en…
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Bioengineering

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JoVE Journal Bioengineering
Vergelijkbare Decellularization van foetale en volwassen cardiale weefsel explantaten als 3D-achtige platformen voor In Vitro Studies
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Vergelijkbare Decellularization van foetale en volwassen cardiale weefsel explantaten als 3D-achtige platformen voor In Vitro Studies

Article DOI: 10.3791/56924-v • 08:10 min • March 21st, 2019
March 21st, 2019 •
1,2,3,4, 1,2,5, 4,6, 1,2,3, 1,2, 1,2,3
1i3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, 2INEB - Instituto de Engenharia Biomédica, Universidade do Porto, 3Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, 4Gladstone Institute of Cardiovascular Disease, 5Faculty of Medicine, University of Porto, 6University of California San Francisco

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De cardiale extracellulaire matrix (ECM) is een complex netwerk van moleculen die orkestreren van belangrijke processen in weefsels en organen terwijl blijvende fysiologische remodelleren gedurende het hele leven. Gestandaardiseerde decellularization van foetale en volwassen hart toelaat vergelijkende experimentele studies van beide weefsels in een 3D-kader door het vastleggen van inheemse architectuur en biomechanische eigenschappen.

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Bioengineering kwestie 145 Decellularization extracellulaire matrix 3D steigers foetale hart volwassen hart cardiale weefselengineering
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