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JoVE Journal
Immunology and Infection

This content is Open Access.

Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice
 

Visualizing Leukocyte Rolling and Adhesion in Angiotensin II-Infused Mice: Techniques and Pitfalls

Article doi: 10.3791/56948
January 4th, 2018

Summary January 4th, 2018

This manuscript describes the use of transgenic reporter mice and different administration routes of fluorescent dyes in angiotensin II-induced hypertension using intravital video microscopy of blood vessels to evaluate the activation of immune cells and their ability to roll and adhere to the endothelium.

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