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Cancer Research

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Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres
 

Native Chromatin Immunoprecipitation Using Murine Brain Tumor Neurospheres

Article doi: 10.3791/57016
January 29th, 2018

Summary January 29th, 2018

Epigenetic mechanisms are frequently altered in glioma. Chromatin immunoprecipitation could be used to study the consequences of genetic alterations in glioma that result from changes in histone modifications which regulate chromatin structure and gene transcription. This protocol describes native chromatin immunoprecipitation on murine brain tumor neurospheres.

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