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JoVE Journal
Bioengineering

This content is Open Access.

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material
 

Optimization of a Multiplex RNA-based Expression Assay Using Breast Cancer Archival Material

Article DOI: 10.3791/57148
August 1st, 2018

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Summary August 1st, 2018

Nucleic acid degradation in archival tissue, tumor heterogeneity, and a lack of fresh frozen tissue specimens can negatively impact cancer diagnostic services in pathology laboratories worldwide. This manuscript describes the optimization of a panel of biomarkers using a multiplex magnetic bead assay to classify breast cancers.

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