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Cancer Research

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JoVE Journal Cancer Research
A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay
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Journal (Cancer Research)
Generation of 3D Tumor Spheroids for Drug Evaluation Studies
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A Comprehensive Procedure to Evaluate the In Vitro Performance of the Putative Hemangioblastoma Neovascularization Using the Spheroid Sprouting Assay

Article DOI: 10.3791/57183-v • 08:26 min • April 12th, 2018
April 12th, 2018 •
1, 1, 1, 1, 1, 1
1Department of Neurosurgery, Huashan Hospital, Fudan University

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Summary
Automatic Translation

This paper presents a comprehensive procedure to evaluate in vitro whether classic tumor angiogenesis exists in hemangioblastomas (HBs) and its role in HBs. The results highlight the complexity of HB-neovascularization and suggest that this common form of angiogenesis is only a complementary mechanism in the HB-neovascularization.

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Comprehensive Procedure Evaluate In Vitro Performance Putative Hemangioblastoma Neovascularization Spheroid Sprouting Assay Angiogenic Field Tumor Angiogenesis Classic Tumor Angiogenesis Hemangioblastoma Growth Therapy Of Hemangioblastoma Vasculaturement Complexity Of Hemangioblastoma Neovascularization Common Form Of Angiogenesis Complementary Mechanism Insight Into Study Tumors Angiogenesis Vasculogenesis Related Application Tumor Vasculogenic Mimicry Glass Tumor Demonstration Of Method Manipulated Endothelial Cell Spheroid Step Suitable Conditions
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