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JoVE Journal
Developmental Biology

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Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery
 

Using Human Induced Pluripotent Stem Cell-derived Hepatocyte-like Cells for Drug Discovery

Article DOI: 10.3791/57194
May 19th, 2018

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Summary May 19th, 2018

The protocol presented here describes a platform for identifying small molecules for the treatment of liver disease. A step-by-step description is presented detailing how to differentiate iPSCs into cells with hepatocyte characteristics in 96-well plates, and to use the cells to screen for small molecules with potential therapeutic activity.

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