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JoVE Journal
Bioengineering

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JoVE Journal Bioengineering
Perfusable Vascular Network with a Tissue Model in a Microfluidic Device
 

Perfusable Vascular Network with a Tissue Model in a Microfluidic Device

Article doi: 10.3791/57242
April 4th, 2018 •
1, 1, 1, 2, 3, 3, 1, 3, 2, 1
1Department of Micro Engineering, Kyoto University, 2Graduate School of Medical Sciences, Kyushu University, 3International Research Center for Medical Sciences (IRCMS), Kumamoto University

Summary
Automatic Translation
April 4th, 2018

The protocol describes how to engineer a perfusable vascular network in a spheroid. The spheroid's surrounding microenvironment is devised to induce angiogenesis and connect the spheroid to the microchannels in a microfluidic device. The method allows the perfusion of the spheroid, which is a long-awaited technique in three-dimensional cultures.

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