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JoVE Journal
Bioengineering

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Perfusable Vascular Network with a Tissue Model in a Microfluidic Device
 

Perfusable Vascular Network with a Tissue Model in a Microfluidic Device

Article DOI: 10.3791/57242
April 4th, 2018

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Summary April 4th, 2018

The protocol describes how to engineer a perfusable vascular network in a spheroid. The spheroid's surrounding microenvironment is devised to induce angiogenesis and connect the spheroid to the microchannels in a microfluidic device. The method allows the perfusion of the spheroid, which is a long-awaited technique in three-dimensional cultures.

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