Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

DOI:

10.3791/57297-v

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07:30 min

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March 07, 2018

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Jorge T. Dias, Gustav Svedberg, Mats Nystrand, Helene Andersson-Svahn, Jesper Gantelius

¹Division of Proteomics and Nanobiotechnology, Science for Life Laboratory,KTH Royal Institute of Technology, ²Global Research and Development,Thermo Fisher Scientific IDD

Chapters

00:04Title
00:33Functionalization of Gold Nanoparticles (AuNPs)
03:32Enhancement of Vertical Flow Paper-based Assays
05:50Results: Signal Enhancement of IgG-modified AuNPs, AgNPs, SiNPs, and IONPs
07:13Conclusion

Summary

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In this work, a protocol for signal enhancement of nanoprobe-based biosensing is presented. The protocol is based on the reduction of chloroauric acid onto the surface of existing nanoprobes that consist of gold, silver, silica or iron-oxide nanoparticles.

Rapid Nanoprobe Signal Enhancement by In Situ Gold Nanoparticle Synthesis

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