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Cancer Research

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Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation
 

Dual Effects of Melanoma Cell-derived Factors on Bone Marrow Adipocytes Differentiation

Article DOI: 10.3791/57329
August 23rd, 2018

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Summary August 23rd, 2018

Here, we present a reliable and straightforward two-dimensional (2D) coculture system for studying the interaction between tumor cells and bone marrow adipocytes, which reveals a dual effect of melanoma cell-derived factors on the bone marrow adipocytes differentiation and also poses a classic method for the mechanistic study of bone metastasis.

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