Login processing...

Trial ends in Request Full Access Tell Your Colleague About Jove
JoVE Journal
Medicine

A subscription to JoVE is required to view this content.
You will only be able to see the first 20 seconds.

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice
 

A Closed-chest Model to Induce Transverse Aortic Constriction in Mice

Article doi: 10.3791/57397
April 5th, 2018

Summary April 5th, 2018

Here, we present a protocol of Transverse Aortic constriction (TAC) via a lateral thoracotomy. This technique is a minimally invasive, closed chest surgical procedure aiming to simulate pressure overload and heart failure in mice utilizing standard TAC laboratory settings.

Transcript

Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
simple hit counter