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JoVE Journal Cancer Research
Generatie van High-Throughput driedimensionale Tumor spheroïden voor Drug Screening
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Generatie van High-Throughput driedimensionale Tumor spheroïden voor Drug Screening

Article DOI: 10.3791/57476-v • 05:54 min • September 5th, 2018
September 5th, 2018 •
1, 1, 2, 2, 2, 2, 2, 1
1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research

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Over een breed scala van indicaties van de ziekte, meer fysiologisch relevante modellen worden ontwikkeld en uitgevoerd in drug discovery-programma's. Het nieuwe modelsysteem hier beschreven demonstreert hoe driedimensionale tumor spheroïden kunnen worden gekweekt en vertoond in een high-throughput 1536-well plaat-gebaseerd systeem om te zoeken naar nieuwe oncologie drugs.

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Kankeronderzoek kwestie 139 Tumor spheroïden driedimensionale (3D) multi goed platen drug screening high-throughput gedefinieerde medium
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