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JoVE Journal Cancer Research
Geração de esferoides Tumor tridimensional de alta produtividade para triagem de drogas
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Geração de esferoides Tumor tridimensional de alta produtividade para triagem de drogas

Article DOI: 10.3791/57476-v • 05:54 min • September 5th, 2018
September 5th, 2018 •
1, 1, 2, 2, 2, 2, 2, 1
1Oncology Drug Discovery: Molecular Pharmacology, Novartis Institutes for Biomedical Research, 2Chemical Biology and Therapeutics, Novartis Institutes for Biomedical Research

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Uma grande variedade de indicações de doença, modelos mais fisiologicamente relevantes estão sendo programas de descoberta de drogas desenvolvida e implementada em. O novo sistema de modelo aqui descrito demonstra como tridimensional tumor esferoides podem ser cultivadas e exibidos em um sistema de baseado em placa de 1536-bem elevado-throughput para pesquisar novas drogas de Oncologia.

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Pesquisa sobre o câncer edição 139 Tumor esferoides tridimensional (3D) multi bem as placas meio de triagem de alto rendimento definido de drogas
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